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Tocris Bioscience™ LP 922056

Notum inhibitor; activates Wnt signaling

Manufacturer:  Tocris Bioscience™ 6691/50

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Catalog No. 66-915-0


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Description

Description

LP 922056 is a notum pectinacetylesterase inhibitor. LP 922056 activates wnt signaling in vitro (EC50 values are 21 nM in human and 55 nM in mouse cell-based assay). It increases cortical bone thickness in mouse model of bone growth. LP 922056 also inhibits growth of Apc-mutant cell lines and proliferation of intestinal adenomas in vivo.
Specifications

Specifications

2-[(6-Chloro-7-cyclopropylthieno[3,2-d]pyrimidin-4-yl)thio]acetic acid
98%
50 mg
C11H9ClN2O2S2
1365060-22-5
SDS
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