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  5. Tocris Bioscience™ LP 99

Tocris Bioscience™ LP 99
GREENER_CHOICE

Catalog No. 549625
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective BRD7 and BRD9 inhibitor (Kd values are 99 and 909 nM, respectively)

LP 99 is a selective BRD7 and BRD9 inhibitor (Kd values are 99 and 909 nM, respectively) that exhibits selectivity for BRD7/9 over a panel of 48 bromodomains (at 10 μM). LP 99 inhibits interactions with histones H3.3 and H4 at low micromolar concentrations, and decreases the level of IL-6 secreted from LPS-stimulated THP-1 cells, in vitro. A negative control for LP 99, ent-LP 99 (Cat.No. 5497), is also available.

Specifications

Chemical Name or Material N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide
CAS 1808951-93-0
Quantity 25 mg
Molecular Formula C26H30ClN3O4S
Formula Weight 516.05
Purity 98%
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