Invitrogen™ LPAM-1 Monoclonal Antibody (DATK32), PE

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MLPAM104

Catalog No. 50-113-7527

Description

LPAM-1 Monoclonal Antibody for Flow

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

Specifications

• Antigen: LPAM-1
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with <0.1% sodium azide; pH 7.5
• Gene Accession No.: P26011, Q00651
• Gene Symbols: Itga4, Itgb7
• Immunogen: Mouse LPAM-1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: DATK32
• Conjugate: PE
• Gene: Itgb7
• Gene Alias: CD49 antigen-like family member D; CD49D; integrin alpha 4; integrin alpha-4; integrin alpha4B; Integrin alpha-IV; integrin beta 7; integrin beta-7; Integrin beta-P; Itga4; Itga4B; Itgb7; LPAM subunit alpha; Ly69; lymphocyte Peyer patch adhesion molecules subunit alpha; M290 IEL antigen; VLA; VLA 4; VLA-4 receptor, alpha 4 subunit; VLA4 subunit alpha; VLA-4 subunit alpha
• Host Species: Rat
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 16401, 16421
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid