LPAP Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7629	100 μL

Catalog No. 50-198-7629 Supplier Bioss Supplier No. BS6963R

Description

Rabbit Polyclonal Antibody

MSK-1 is a mitogen and stress activated protein kinase-1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK-1 can be activated by ERK1/2 and SAPK2 /p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG-14 in response to mitogen and stress. Similar to RSK, MSK-1 contains two kinase domains (N-term and a C-term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C-terminal kinase domain of MSK-1 which is essential for the catalytic activity of the N-terminal kinase domain.

Specifications

• Antigen: LPAP
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: PTPRCAP
• Gene Accession No.: Q14761
• Gene Alias: CD45 associated protein; CD45-AP; CD45-associated protein; LPAP; Lymphocyte phosphatase-associated phosphoprotein; Protein tyrosine phosphatase receptor type C-associated protein; protein tyrosine phosphatase, receptor type C associated protein; protein tyrosine phosphatase, receptor type, c polypeptide-associated protein; protein tyrosine phosphatase, receptor type, C-associated protein; PTPRCAP; PTPRC-associated protein
• Gene Symbols: PTPRCAP
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human LPAP.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5790
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG