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Invitrogen™ LPHN2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533905

Catalog No. PIPA533905


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Description

Description

Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (100%) Gorilla, Marmoset, Mouse (94%) Rat, Dog, Panda (88%).

The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

LPHN2
Polyclonal
Unconjugated
ADGRL2
Adgrl2; Adhesion G protein-coupled receptor L2; AI450192; Calcium-independent alpha-latrotoxin receptor 2; calcium-independent alpha-latrotoxin receptor homolog 2; Cirl2; Cirl-2; Cl2; Cl2aa; Cl2ac; Gm619; KIAA0786; latrophilin 1; latrophilin 2; latrophilin homolog 1; Latrophilin-2; LEC1; Lectomedin-1; LPHH1; Lphn2; mKIAA0786
Rabbit
Antigen Affinity Chromatography
RUO
23266
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 0.1% sodium azide
O95490
ADGRL2
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN2.
50 μg
Primary
Human
Antibody
IgG
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