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Invitrogen™ LPHN2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA533905
Description
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (100%) Gorilla, Marmoset, Mouse (94%) Rat, Dog, Panda (88%).
The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
Specifications
LPHN2 | |
Polyclonal | |
Unconjugated | |
ADGRL2 | |
Adgrl2; Adhesion G protein-coupled receptor L2; AI450192; Calcium-independent alpha-latrotoxin receptor 2; calcium-independent alpha-latrotoxin receptor homolog 2; Cirl2; Cirl-2; Cl2; Cl2aa; Cl2ac; Gm619; KIAA0786; latrophilin 1; latrophilin 2; latrophilin homolog 1; Latrophilin-2; LEC1; Lectomedin-1; LPHH1; Lphn2; mKIAA0786 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
23266 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
1 mg/mL | |
PBS with 0.1% sodium azide | |
O95490 | |
ADGRL2 | |
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human LPHN2. | |
50 μg | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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