Invitrogen™ LRBA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553986

Catalog No. PIPA553986

Description

Immunogen sequence: SVLMVSKYRD ILEPQNERHS QSCTETGSEN ENVSLSEITP AAFSTLTTAS VEESESTSSA RRRDSGIGEE TATGLGSHVE VTPHTAPPGV SAGPDAISEV LSTLSLEVNK SPETKNDRGN DLDTKATPSV SV Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 73%.

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: LRBA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRBA
• Gene Alias: Beige-like protein; BGL; CDC4L; CDC4-like protein; CVID8; LAB300; LBA; Lipopolysaccharide-responsive and beige-like anchor protein; LPS responsive beige-like anchor protein; LPS-responsive vesicle trafficking, beach and anchor containing; LRBA; vesicle trafficking, beach and anchor containing
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 987
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P50851
• Gene Symbols: LRBA
• Immunogen: Recombinant protein corresponding to Human LRBA. Recombinant protein control fragment (Product #RP-92444).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG