Invitrogen™ LRFN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520698

Catalog No. PIPA520698

Description

A suggested positive control is human brain tissue lysate. PA5-20698 can be used with blocking peptide PEP-0813.

LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN1 are known to exist.

Specifications

• Antigen: LRFN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRFN1
• Gene Alias: BC004018; CTC-246B18.8; KIAA1484; leucine rich repeat and fibronectin type III domain containing 1; leucine-rich repeat and fibronectin type III domain-containing protein 1; Lrfn1; Salm2; Semo1; Synaptic adhesion-like molecule 2; synaptic differentiation enhancing molecule 1; synaptic differentiation-enhancing molecule 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 365222, 57622, 80749
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P0C7J6, Q2WF71, Q9P244
• Gene Symbols: LRFN1
• Immunogen: An 18 amino acid peptide near the carboxy terminus of human LRFN1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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