Invitrogen™ LRFN3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561839

Catalog No. PIPA561839

Description

Immunogen sequence: EATAAVELTV GPPPPPQLAN STSCDPPRDG DPDALTPPSA AS Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.

Specifications

• Antigen: LRFN3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRFN3
• Gene Alias: A530045B06Rik; EMBL:AAI58863.1, ECO:0000312; fibronectin type III, immunoglobulin and leucine rich repeat domains 1; FIGLER1; leucine rich repeat and fibronectin type III domain containing 3; leucine-rich repeat and fibronectin type-III domain-containing protein 3; LRFN3; lrfn3 {ECO:0000312; PubMed:18227064}; RGD:1305567}; Salm4; Synaptic adhesion-like molecule 4; synaptic adhesion-like molecule 4 {ECO:0000303; UNQ5865/PRO34192
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79414
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BTN0
• Gene Symbols: LRFN3
• Immunogen: Recombinant protein corresponding to Human LRFN3. Recombinant protein control fragment (Product #RP-100946).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG