Invitrogen™ LRFN3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520706

Catalog No. PIPA520706

Description

A suggested positive control is K562 cell lysate. PA5-20706 can be used with blocking peptide PEP-0821.

LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.

Specifications

• Antigen: LRFN3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRFN3
• Gene Alias: A530045B06Rik; EMBL:AAI58863.1, ECO:0000312; fibronectin type III, immunoglobulin and leucine rich repeat domains 1; FIGLER1; leucine rich repeat and fibronectin type III domain containing 3; leucine-rich repeat and fibronectin type-III domain-containing protein 3; LRFN3; lrfn3 {ECO:0000312; PubMed:18227064}; RGD:1305567}; Salm4; Synaptic adhesion-like molecule 4; synaptic adhesion-like molecule 4 {ECO:0000303; UNQ5865/PRO34192
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 233067, 308495, 79414
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: B0BNK7, Q8BLY3, Q9BTN0
• Gene Symbols: LRFN3
• Immunogen: A 16 amino acid peptide near the center of human LRFN3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG