Invitrogen™ LRFN4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140294

Catalog No. PIPA5140294

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: GEGTLESEPA VQVTEVTATS GLVSWGPGRP ADPVWMFQIQ YNSSEDETLI YRIVPASSHH FLLKHLVPGA DYDLC.

LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. At least two isoforms of LRFN4 are known to exist.

Specifications

• Antigen: LRFN4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRFN4
• Gene Alias: BC023156; fibronectin type III, immunoglobulin and leucine rich repeat domains 6; FIGLER6; leucine rich repeat and fibronectin type III domain containing 4; leucine-rich repeat and fibronectin type-III domain-containing protein 4; Lrfn4; Salm3; SALM3.; synaptic adhesion-like molecule 3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 78999
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6PJG9
• Gene Symbols: LRFN4
• Immunogen: Recombinant protein corresponding to Human LRFN4. Recombinant protein control fragment (Product #RP-109634).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG