Invitrogen™ LRIG1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588302

Catalog No. PIPA588302

Description

Immunogen sequence: YQTRKKSEEY SVTNTDETVV PPDVPSYLSS QGTLSDRQET VVRTEGGPQA NGHIESNGVC PRDASHFPEP DTHSVACRQP KLCAGSAYHK EPWKAMEKAE GTPGPHKMEH GGRVVCSDCN TEVDCYSRGQ AFHPQPVSRD SAQPSAPNGP EPGGSDQEHS PHHQCSRTAA GSCPECQGSL YPSNHDRMLT AVKKKPMASL DGKGDSSWTL ARLYHPDSTE LQPASSLTSG SPERAEAQYL LVSNGHLPKA CDASPESTPL TGQLPGKQRV PLLLAPKS; Positive Samples: Raji, HeLa; Cellular Location: Membrane, Single-pass type I membrane protein.

LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.

Specifications

• Antigen: LRIG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Lrig1
• Gene Alias: D6Bwg0781e; DKFZp586O1624; Img; integral membrane glycoprotein; leucine rich repeats and immunoglobulin like domains 1; leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin like domains 1; leucine-rich repeats and immunoglobulin-like domains 1; leucine-rich repeats and immunoglobulin-like domains protein 1; LIG1; LIG-1; LRIG1; ortholog of mouse integral membrane glycoprotein LIG-1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26018
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q96JA1
• Gene Symbols: Lrig1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_0563562).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG