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Invitrogen™ LRIG1 Polyclonal Antibody
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Catalog No. PIPA588302
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100 μL
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PIPA588302 100 μL
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Catalog No. PIPA588302 Supplier Invitrogen™ Supplier No. PA588302
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YQTRKKSEEY SVTNTDETVV PPDVPSYLSS QGTLSDRQET VVRTEGGPQA NGHIESNGVC PRDASHFPEP DTHSVACRQP KLCAGSAYHK EPWKAMEKAE GTPGPHKMEH GGRVVCSDCN TEVDCYSRGQ AFHPQPVSRD SAQPSAPNGP EPGGSDQEHS PHHQCSRTAA GSCPECQGSL YPSNHDRMLT AVKKKPMASL DGKGDSSWTL ARLYHPDSTE LQPASSLTSG SPERAEAQYL LVSNGHLPKA CDASPESTPL TGQLPGKQRV PLLLAPKS; Positive Samples: Raji, HeLa; Cellular Location: Membrane, Single-pass type I membrane protein.

LRIG1 protein Q96JA1 is coded by a gene on a chromosome band 3p14.3, this region is known to be deleted in various human cancers. LRIG1 is considered to be a tumor suppressor gene in humans. LRIG1 is an integral cell-surface membrane protein that is expressed by specific cells in various human tissues and that its 143-kDa form might be cleaved into 111-kDa and 32-kDa fragments. The LRIG1 protein may inhibit the growth of tumors of glial cells and the down-regulation of the LRIG1 gene may be involved in the development and progression of the tumor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRIG1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.32 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Lrig1
Gene Accession No. Q96JA1
Gene Alias D6Bwg0781e; DKFZp586O1624; Img; integral membrane glycoprotein; leucine rich repeats and immunoglobulin like domains 1; leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin like domains 1; leucine-rich repeats and immunoglobulin-like domains 1; leucine-rich repeats and immunoglobulin-like domains protein 1; LIG1; LIG-1; LRIG1; ortholog of mouse integral membrane glycoprotein LIG-1
Gene Symbols Lrig1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 816-1093 of human LRIG1 (NP_0563562).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26018
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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