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Invitrogen™ LRP12 Isoform A Precursor Polyclonal Antibody
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Catalog No. PIPA5104431
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PIPA5104431 100 μL
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Catalog No. PIPA5104431 Supplier Invitrogen™ Supplier No. PA5104431
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total LRP12.

Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2 are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP12, also designated ST7, is a member of the LDLR family that is thought to be involved in the internalization of lipophilic molecules and/or signal transduction. LRP12 has been shown to interact with RACK1, MADHIP and Integrin beta-1-binding protein 3. It is widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. Overexpression of LRP12 may be associated with oral tumors, therefore implicating LRP12 as a potential oncogene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRP12 Isoform A Precursor
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene LRP12
Gene Accession No. Q9Y561
Gene Alias LDL receptor related protein 12; LDLR-related protein 12; low density lipoprotein receptor-related protein 12; low-density lipoprotein receptor-related protein 12; LRP12; ST7; Suppressor of tumorigenicity 7 protein
Gene Symbols LRP12
Host Species Rabbit
Immunogen A synthesized peptide derived from human LRP12(Accession Q9Y561), corresponding to amino acid residues T408-C458.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29967
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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