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Invitrogen™ LRP5 Monoclonal Antibody (2B11)
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Catalog No. PIMA517113
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100 μg
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Catalog No. Quantity
PIMA517113 100 μg
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Catalog No. PIMA517113 Supplier Invitrogen™ Supplier No. MA517113
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Description

Mouse Monoclonal Antibody

MA5-17113 targets LRP5 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17113 immunogen is purified recombinant fragment of human LRP5 expressed in E. Coli. MA5-17113 detects LRP5 which has a predicted molecular weight of approximately 179kDa.

LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRP5
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 2B11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene LRP5
Gene Accession No. O75197
Gene Alias BMND1; EVR1; EVR4; HBM; HGNC:6697; LDL receptor related protein 5; low density lipoprotein receptor-related protein 5; low density lipoprotein receptor-related protein 7; low-density lipoprotein receptor-related protein 5; Low-density lipoprotein receptor-related protein 7; LR3; Lrp5; LRP-5; LRP7; LRP-7; mKIAA4142; OPPG; OPS; OPTA1; VBCH2
Gene Symbols LRP5
Host Species Mouse
Immunogen Purified recombinant fragment of human LRP5 expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4041
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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