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Invitrogen™ LRP5 Polyclonal Antibody
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Catalog No. PIPA587357
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100 μL
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PIPA587357 100 μL
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Catalog No. PIPA587357 Supplier Invitrogen™ Supplier No. PA587357
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse liver, Rat liver; Cellular Location: Endoplasmic reticulum, Membrane, Single-pass type I membrane protein Immunogen sequence: YAGANGPFPH EYVSGTPHVP L.

LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRP5
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.69 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene LRP5
Gene Accession No. Q91VN0
Gene Alias BMND1; EVR1; EVR4; HBM; HGNC:6697; LDL receptor related protein 5; low density lipoprotein receptor-related protein 5; low density lipoprotein receptor-related protein 7; low-density lipoprotein receptor-related protein 5; Low-density lipoprotein receptor-related protein 7; LR3; Lrp5; LRP-5; LRP7; LRP-7; mKIAA4142; OPPG; OPS; OPTA1; VBCH2
Gene Symbols LRP5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human LRP5 (NP_0023262).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16973, 293649
Target Species Mouse, Rat, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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