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LRP5 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985910
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100 μL
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Catalog No. Quantity
50-198-5910 100 μL
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Catalog No. 50-198-5910 Supplier Bioss Supplier No. BS4117R
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Description

Rabbit Polyclonal Antibody

LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.

Specifications

Antigen LRP5
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene LRP5
Gene Accession No. O75197
Gene Alias BMND1; EVR1; EVR4; HBM; HGNC:6697; LDL receptor related protein 5; low density lipoprotein receptor-related protein 5; low density lipoprotein receptor-related protein 7; Low-density lipoprotein receptor-related protein 5; Low-density lipoprotein receptor-related protein 7; LR3; Lrp5; LRP-5; LRP7; LRP-7; mKIAA4142; OPPG; OPS; OPTA1; VBCH2
Gene Symbols LRP5
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human LRP5.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4041
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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