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Invitrogen™ LRRC15 Polyclonal Antibody
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Catalog No. PIPA557298
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100 μL
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PIPA557298 100 μL
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Catalog No. PIPA557298 Supplier Invitrogen™ Supplier No. PA557298
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NWLLLNQPRL GTDTVPVCFS PANVRGQSLI IINVNVAVPS VHVPEVPSYP ETPWYPDTPS YPDTTSVSST TELTSPVEDY TDLTTIQVTD DRSVW Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 73%.

Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC15
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LRRC15
Gene Accession No. Q8TF66
Gene Alias 5430427N11Rik; hLib; leucine rich repeat containing 15; Leucine-rich repeat protein induced by amyloid-beta; leucine-rich repeat protein induced by beta amyloid; leucine-rich repeat protein induced by beta-amyloid; leucine-rich repeat protein induced by beta-amyloid homolog; Leucine-rich repeat-containing protein 15; LIB; Lrrc15; rLib
Gene Symbols LRRC15
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LRRC15. Recombinant protein control fragment (Product #RP-95705).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 131578
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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