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LRRC15 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA531778
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100 μL
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PIPA531778 100 μL
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Catalog No. PIPA531778 Supplier Thermo Scientific Supplier No. PA531778

Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1. Predicted reactivity: Rat (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC15
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene LRRC15
Gene Accession No. Q8TF66
Gene Alias 5430427N11Rik; hLib; leucine rich repeat containing 15; Leucine-rich repeat protein induced by amyloid-beta; leucine-rich repeat protein induced by beta amyloid; leucine-rich repeat protein induced by beta-amyloid; leucine-rich repeat protein induced by beta-amyloid homolog; Leucine-rich repeat-containing protein 15; LIB; Lrrc15; rLib
Gene Symbols LRRC15
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 23 and 241 of Human LRRC15
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 131578
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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