LRRC16A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA556045

Catalog No. PIPA556045

Description

Immunogen sequence: RSDSKSSPQA GRRYGVQVMG SGLLAEMKAK QEKRAACAQK KLGNDAVSQD SSSPALSSVE RSDGGGAVPK LHPGLPENRF GLGTPEKNTK AEPKAEA Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 77%.

Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667). [UniProt]

Specifications

• Antigen: LRRC16A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CARMIL1
• Gene Alias: 1110037D04Rik; AI425970; capping protein regulator and myosin 1 linker 1; Capping protein regulator and myosin 1 linker protein 1; Capping protein, Arp2/3 and myosin-I linker homolog 1; capping protein, Arp2/3 and myosin-I linker protein 1; capping protein, Arp2/3, and Myosin-I Linker homolog 1; CARMIL; CARMIL homolog; CARMIL1; CARMIL1a; CARML1; D130057M20; dJ501N12.1; dJ501N12.5; F-actin-uncapping protein LRRC16A; leucine rich repeat containing 16; leucine rich repeat containing 16A; leucine-rich repeat-containing protein 16A; Lrrc16; LRRC16A; testicular tissue protein Li 107
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55604
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry
• Concentration: 0.84 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5VZK9
• Gene Symbols: CARMIL1
• Immunogen: Recombinant protein corresponding to Human LRRC16A
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov

Research Use Only