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Invitrogen™ LRRC17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113953

Catalog No. PIPA5113953


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Description

Description

Immunogen sequence: YVFPIQTLDC KRKELKKVPN NIPPDIVKLD LSYNKINQLR PKEFEDVHEL For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%.

Leucine-rich repeat-containing protein 17 (LRRC17) is an LRR protein predominantly expressed by osteoblasts. LRRC17 acts as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. It has been reported that low plasma level of LRRC17 is an independent risk factor for osteoporotic fractures.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

LRRC17
Polyclonal
Unconjugated
LRRC17
37 kDa leucine-rich repeat (LRR) protein; 37kDa; 4833425M04Rik; 6130400C22Rik; leucine rich repeat containing 17; leucine-rich repeat (LRR) protein; leucine-rich repeat-containing protein 17; Lrrc17; p37NB; UNQ3076/PRO9909
Rabbit
Affinity chromatography
RUO
10234
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.5 mg/mL
PBS with 2% sucrose and 0.09% sodium azide
Q8N6Y2
LRRC17
Synthetic peptide directed towards the middle region of human LRRC17.
100 μL
Primary
Human
Antibody
IgG
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