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LRRC19 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982128
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50-198-2128 100 μL
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Catalog No. 50-198-2128 Supplier Bioss Supplier No. BS12310R
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Rabbit Polyclonal Antibody

LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappa-B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.

Specifications

Antigen LRRC19
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene LRRC19
Gene Accession No. Q9H756
Gene Alias 9130022A01Rik; AI314124; AL022954; AW261791; leucine rich repeat containing 19; Leucine-rich repeat-containing protein 19; Lrrc19
Gene Symbols LRRC19
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human LRRC19.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64922
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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