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Invitrogen™ LRRC25 Monoclonal Antibody (OTI1C5)
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Catalog No. PIMA526004
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PIMA526004 100 μL
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Catalog No. PIMA526004 Supplier Invitrogen™ Supplier No. MA526004
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Mouse Monoclonal Antibody

LRRC25 Monoclonal Antibody for Western Blot, Flow

Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164). Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC25
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone OTI1C5
Concentration 1.01 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LRRC25
Gene Accession No. Q8N386
Gene Alias leucine rich repeat containing 25; leucine-rich repeat-containing protein 25; LRRC25; MAPA; monocyte and plasmacytoid activated molecule; monocyte and plasmacytoid-activated protein; UNQ6169/PRO20174
Gene Symbols LRRC25
Host Species Mouse
Immunogen Full length human recombinant protein of LRRC25 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126364
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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