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Invitrogen™ LRRC4B Polyclonal Antibody
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Catalog No. PIPA563638
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100 μL
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PIPA563638 100 μL
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Catalog No. PIPA563638 Supplier Invitrogen™ Supplier No. PA563638
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GTEKEPPGPT TDGVWGGGRP GDAAGPASSS TTAPAPRSSR PTEKAFTVPI TDVTENALKD LDD Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

The LRRC4B gene encodes a protein known as leucine-rich repeat-containing protein 4B, which is involved in cellular signaling and neural development. LRRC4B is a member of the leucine-rich repeat (LRR) protein family, characterized by its ability to mediate protein-protein interactions through its LRR domains. This protein is predominantly expressed in the nervous system and plays a crucial role in neuronal growth, synapse formation, and signal transduction pathways essential for brain development and function. LRRC4B contributes to cell adhesion, growth cone guidance, and synaptic plasticity, influencing the formation and maintenance of neural circuits. Its dysregulation has been linked to neurodevelopmental disorders, highlighting its importance in cognitive functions and neurological health. Additionally, LRRC4B is implicated in cancer biology, where it may act as a tumor suppressor, modulating cellular proliferation and migration. Research continues to explore LRRC4B's interactions and regulatory mechanisms, offering insights into potential therapeutic applications for neurological diseases and cancer.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC4B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LRRC4B
Gene Accession No. Q9NT99
Gene Alias A830007M12; HSM; leucine rich repeat containing 4B; leucine-rich repeat-containing protein 4B; leucine-rich repeats and immunoglobulin-like domains 4; Lrig4; Lrrc4b; Netrin-G3 ligand; NGL-3; protein NGL-3
Gene Symbols LRRC4B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LRRC4B. Recombinant protein control fragment (Product #RP-101924).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 94030
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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