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Invitrogen™ LRRC4C Monoclonal Antibody (755720)
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Catalog No. PIMA524363
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100 μg
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Catalog No. Quantity
PIMA524363 100 μg
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Catalog No. PIMA524363 Supplier Invitrogen™ Supplier No. MA524363
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Description

Mouse Monoclonal Antibody

In direct ELISAs, no cross-reactivity with recombinant human (rh) LRRC4 or rhNGL-3/LRRC4B is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

Leucine-rich repeat-containing 4C (LRRC4C), also known as Netrin-G ligand 2 (NGL-2), is a gene highlighted for its expression in the nervous system, particularly the brain. It is a member of the leucine-rich repeat superfamily, which plays a significant role in cell adhesion and signaling pathways critical for synaptic connectivity and neuronal development. LRRC4C is involved in neural processes such as axon guidance and synapse formation, aiding in the establishment of functional neural circuits. Additionally, research has suggested that LRRC4C may function as a tumor suppressor, particularly in gliomas, indicating its potential role in neuro-oncological disorders. Variations or deletions in this gene have been linked to neurodevelopmental disorders, demonstrating its importance in normal brain function and development. Furthermore, LRRC4C's expression patterns and associations with cancer also suggest its potential as a prognostic marker in clinical settings.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC4C
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 755720
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene LRRC4C
Gene Accession No. Q9HCJ2
Gene Alias 6430556C10Rik; KIAA1580; leucine rich repeat containing 4C; leucine-rich repeat-containing protein 4C; Lrrc4c; Netrin-G1 ligand; NGL1; NGL-1; RGD1311013; UNQ292/PRO331
Gene Symbols LRRC4C
Host Species Mouse
Immunogen Mouse myeloma cell line NS0-derived recombinant human NGL-1/LRRC4C Gln45-Lys527 (predicted).
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57689
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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