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Invitrogen™ LRRC4C Polyclonal Antibody
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Catalog No. PIPA5111400
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PIPA5111400 100 μL
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Catalog No. PIPA5111400 Supplier Invitrogen™ Supplier No. PA5111400
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NVDDEITGDT PMESHLPMPA IEHEHLNHYN SYKSPFNHTT TVNTINSIHS SVHEPLLIRM NSKD Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.

Leucine-rich repeat-containing 4C (LRRC4C), also known as Netrin-G ligand 2 (NGL-2), is a gene highlighted for its expression in the nervous system, particularly the brain. It is a member of the leucine-rich repeat superfamily, which plays a significant role in cell adhesion and signaling pathways critical for synaptic connectivity and neuronal development. LRRC4C is involved in neural processes such as axon guidance and synapse formation, aiding in the establishment of functional neural circuits. Additionally, research has suggested that LRRC4C may function as a tumor suppressor, particularly in gliomas, indicating its potential role in neuro-oncological disorders. Variations or deletions in this gene have been linked to neurodevelopmental disorders, demonstrating its importance in normal brain function and development. Furthermore, LRRC4C's expression patterns and associations with cancer also suggest its potential as a prognostic marker in clinical settings.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC4C
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.20 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LRRC4C
Gene Accession No. Q9HCJ2
Gene Alias 6430556C10Rik; KIAA1580; leucine rich repeat containing 4C; leucine-rich repeat-containing protein 4C; Lrrc4c; Netrin-G1 ligand; NGL1; NGL-1; RGD1311013; UNQ292/PRO331
Gene Symbols LRRC4C
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human LRRC4C. Recombinant protein control fragment (Product #RP-106572).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57689
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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