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Invitrogen™ LRRC8A Polyclonal Antibody
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Catalog No. PIPA5107160
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100 μL
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PIPA5107160 100 μL
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Catalog No. PIPA5107160 Supplier Invitrogen™ Supplier No. PA5107160
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Description

Rabbit Polyclonal Antibody

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8A constitutes a pore-forming subunit or whether it is closely associated with the pore and mediates channel properties such as ion selectivity. Involved in B-cell development: required for the pro-B cell to pre-B cell transition. Also required for T-cell development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRC8A
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene LRRC8A
Gene Accession No. Q8IWT6
Gene Alias AGM5; KIAA1437; leucine rich repeat containing 8 family member A; leucine rich repeat containing 8 family, member A; leucine rich repeat containing 8A; leucine-rich repeat containing 8 family member A; leucine-rich repeat-containing 8; leucine-rich repeat-containing protein 8A; Lrrc8; LRRC8A; mKIAA1437; SWELL1; Swelling protein 1; UNQ221/PRO247; Volume-regulated anion channel subunit LRRC8A
Gene Symbols LRRC8A
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N terminal region of human LRRC8A.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56262
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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