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Invitrogen™ LRRFIP1 Polyclonal Antibody
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Catalog No. PIPA523445
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100 μg
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Catalog No. Quantity
PIPA523445 100 μg
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Catalog No. PIPA523445 Supplier Invitrogen™ Supplier No. PA523445
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Description

Rabbit Polyclonal Antibody

LRRFIP1 Polyclonal Antibody for Western Blot

Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRFIP1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene LRRFIP1
Gene Accession No. Q32MZ4, Q3UZ39
Gene Alias AU024550; Flap; FLAP (FLI LRR associated protein); FLAP1; flap-1; Fliiap1; FLI-LRR-associated protein 1; GC-binding factor 2; GCF2; GCF-2; H186 FLAP; HUFI1; HUFI-1; leucine rich repeat (in FLII) interacting protein 1; leucine-rich repeat flightless-interacting protein 1; LRR binding FLII interacting protein 1; LRR FLII-interacting protein 1; Lrrfip1; NEDD8-conjugating enzyme; TAR RNA-interacting protein; TRIP
Gene Symbols LRRFIP1
Host Species Rabbit
Immunogen A portion of amino acid 200 to 250 of human LRRFIP1.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16978, 9208
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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