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LRRFIP1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501564210
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Catalog No. Quantity
50-156-4210 20 μL
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Catalog No. 50-156-4210 Supplier Bethyl Laboratories, Inc Supplier No. A303080AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases.

Specifications

Antigen LRRFIP1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene LRRFIP1
Gene Accession No. Q32MZ4
Gene Alias FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP; GC-binding factor 2; LRR FLII-interacting protein 1; NEDD8-conjugating enzyme; TAR RNA-interacting protein; leucine-rich repeat flightless-interacting protein 1
Gene Symbols LRRFIP1
Host Species Rabbit
Immunogen Between 758 and 808
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9208
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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