LRRFIP1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2243	100 μL

Catalog No. 50-198-2243 Supplier Bioss Supplier No. BS12439R

Description

Rabbit Polyclonal Antibody

Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein which mediates either induction or repression of TLR signaling. Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity. Flap-1 or LRRFIP1 was also shown to bind the TNF- -308 promoter polymorphism site, suggesting its possible role in the regulation of TNF- production. FLAP-1 along with LRRFIP2 and FLIIH serve as a balance in coordinating inflammatory response after infection, and may act as a novel target in the control of agonist-induced TLR-mediated inflammatory and autoimmune diseases.

Specifications

• Antigen: LRRFIP1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: LRRFIP1
• Gene Accession No.: Q32MZ4
• Gene Alias: AU024550; BOS_3897; Flap; FLAP (FLI LRR associated protein); FLAP1; Flap-1; FLIIAP1; FLI-LRR-associated protein 1; GC-binding factor 2; GCF2; GCF-2; H186 FLAP; HUFI1; HUFI-1; leucine rich repeat (in FLII) interacting protein 1; leucine rich repeat (in FLII) interacting protein 1-like; Leucine-rich repeat flightless-interacting protein 1; LOC100342928; LRR binding FLII interacting protein 1; LRR FLII-interacting protein 1; Lrrfip1; NEDD8-conjugating enzyme; TAR RNA-interacting protein; TRIP
• Gene Symbols: LRRFIP1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human LRRFIP1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9208
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG