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Invitrogen™ LRRFIP2 Polyclonal Antibody
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Catalog No. PIPA523458
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100 μg
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PIPA523458 100 μg
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Catalog No. PIPA523458 Supplier Invitrogen™ Supplier No. PA523458
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Rabbit Polyclonal Antibody

LRRFIP2 Polyclonal Antibody for IHC (P)

The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRFIP2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene LRRFIP2
Gene Accession No. Q9Y608
Gene Alias 5133400F20Rik; AI850587; HUFI-2; leucine rich repeat (in FLII) interacting protein 2; leucine-rich repeat flightless-interactin protein 2-like protein; leucine-rich repeat flightless-interacting protein 2; LRR binding FLII interacting protein 2; LRR FLII-interacting protein 2; LRRFIP2
Gene Symbols LRRFIP2
Host Species Rabbit
Immunogen Partial synthetic peptide between amino acids 150-210 of human LRRFIP2.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100050285, 9209
Target Species Human, Monkey, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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