Invitrogen™ LRRFIP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA583587

Catalog No. PIPA583587

Description

Immunogen sequence: VKTGEKHGLV IIPDGTPNGD VSHEPVAGAI TVVSQEAAQV LESAGEGPLD VRLRKLAGEK EELLSQIRKL KLQLEEERQK CSRNDGTVGD LA.

The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.

Specifications

• Antigen: LRRFIP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRRFIP2
• Gene Alias: 5133400F20Rik; AI850587; HUFI-2; leucine rich repeat (in FLII) interacting protein 2; leucine-rich repeat flightless-interactin protein 2-like protein; leucine-rich repeat flightless-interacting protein 2; LRR binding FLII interacting protein 2; LRR FLII-interacting protein 2; LRRFIP2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9209
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y608
• Gene Symbols: LRRFIP2
• Immunogen: Recombinant protein corresponding to Human LRRFIP2. Recombinant protein control fragment (Product #RP-104750).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG