Invitrogen™ LRRFIP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599092

Catalog No. PIPA599092

Description

LRRFIP2 Polyclonal Antibody for Western Blot, IHC (P), ELISA

The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.

Specifications

• Antigen: LRRFIP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRRFIP2
• Gene Alias: 5133400F20Rik; AI850587; HUFI-2; leucine rich repeat (in FLII) interacting protein 2; leucine-rich repeat flightless-interactin protein 2-like protein; leucine-rich repeat flightless-interacting protein 2; LRR binding FLII interacting protein 2; LRR FLII-interacting protein 2; LRRFIP2
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 9209
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q9Y608
• Gene Symbols: LRRFIP2
• Immunogen: Recombinant Human Leucine-rich repeat flightless-interacting protein 2 protein (211-342AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG