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LRRFIP2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982242
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100 μL
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50-198-2242 100 μL
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Catalog No. 50-198-2242 Supplier Bioss Supplier No. BS12438R
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Rabbit Polyclonal Antibody

The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-kappa-B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.

Specifications

Antigen LRRFIP2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene LRRFIP2
Gene Accession No. Q9Y608
Gene Alias 5133400F20Rik; AI850587; HUFI-2; leucine rich repeat (in FLII) interacting protein 2; Leucine-rich repeat flightless-interacting protein 2; LRR binding FLII interacting protein 2; LRR FLII-interacting protein 2; LRRFIP2
Gene Symbols LRRFIP2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human LRRFIP2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9209
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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