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Invitrogen™ LRRK2 Polyclonal Antibody
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Catalog No. 01670143
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100 μL
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Catalog No. Quantity
01-670-143 100 μL
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Catalog No. 01-670-143 Supplier Invitrogen™ Supplier No. PA116990
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Description

Rabbit Polyclonal Antibody

Suggested positive control: mouse brain lysate, mouse brain protein.

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson's disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRK2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.09 mg/mL
Conjugate Unconjugated
Formulation Phosphate, tris citrate with 0.1% sodium azide; pH 7-8
Gene LRRK2
Gene Accession No. Q5S006, Q5S007
Gene Alias 4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2
Gene Symbols LRRK2
Host Species Rabbit
Immunogen A synthetic peptide made to an internal region of the mouse LRRK2 protein sequence (between residues 900-1000).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 120892, 66725
Target Species Human, Mouse
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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