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Invitrogen™ LRRK2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA116990
Description
Suggested positive control: mouse brain lysate, mouse brain protein.
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson's disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.
Specifications
LRRK2 | |
Polyclonal | |
Unconjugated | |
LRRK2 | |
4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
66725 | |
4°C, do not freeze | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1.09 mg/mL | |
phosphate, tris citrate with 0.1% sodium azide; pH 7-8 | |
Q5S006 | |
LRRK2 | |
Synthetic peptide corresponding to residues 900-1000 of mouse LRRK2. | |
100 μL | |
Primary | |
Mouse | |
Antibody | |
IgG |
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