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  4. Thermo Scientific™ Human LRRK2, GST Tag Recombinant Protein 

Thermo Scientific™ Human LRRK2, GST Tag Recombinant Protein

Catalog No. PV4873
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Quantity:
1 mg
10 μg
100 μg

Description

Recombinant Protein

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson's disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q5S007
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris with 0.02% polysorbate 20, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 120892
Molecular Weight (g/mol) 204.9 kDa
Name Human LRRK2, GST Tag
Quantity 10 μg
Gene Alias 4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2
Common Name LRRK2
KinaseFamily LRRK Kinase Family
Protein Length 970-2527
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical ADP accumulation, Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group Ser⁄Thr Kinases: TKL Group
Shipping Condition Dry Ice
System Compatibility LanthaScreen™ Antibody, LanthaScreen™ Substrate, Adapta™
Target Entry LRRK2
Target Gene Leucine-rich repeat kinase 2
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Catalytic
Form Liquid
Protein Subtype Serine/Threonine Kinases
Research Category Signal Transduction, Neurobiology
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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