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Invitrogen™ LRRN1 Polyclonal Antibody
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Catalog No. PIPA547684
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100 μg
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PIPA547684 100 μg
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Catalog No. PIPA547684 Supplier Invitrogen™ Supplier No. PA547684
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Description

Sheep Polyclonal Antibody

In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human NLRR-3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Leucine-rich repeat neuronal 1 (LRRN1) is a gene located on chromosome 3q23, which encodes a transmembrane protein belonging to the leucine-rich repeat (LRR) family. This protein plays a significant role in neural development and synaptic plasticity due to its involvement in cell-cell adhesion and signaling pathways. LRRN1 has been implicated in brain development processes, especially in synapse organization and neuronal differentiation. Its expression is primarily localized to the central nervous system, indicating its importance in neurodevelopmental functions. Research has highlighted LRRN1's potential involvement in cognitive functions, and alterations in its expression have been associated with various neurological disorders. Additionally, LRRN1 is thought to contribute to the establishment of neuronal networks by modulating interactions between neurons through extracellular matrix components. Current studies are exploring its contributions to neuropathological conditions, providing insights into its relevance in brain health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRN1
Applications Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene LRRN1
Gene Accession No. Q61809, Q6UXK5
Gene Alias 2810047E21Rik; fibronectin type III, immunoglobulin and leucine rich repeat domains 3; FIGLER3; Kiaa1497; leucine rich repeat neuronal 1; leucine rich repeat protein 1, neuronal; leucine-rich repeat neuronal protein 1; LRN; Lrrn1; Nbla10449; Neuronal leucine-rich repeat protein 1; NLRR-1; UNQ693/PRO1338
Gene Symbols LRRN1
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant human LRRN1 Ser26-Ala631.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16979, 57633
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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