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Invitrogen™ LRRN1 Polyclonal Antibody
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Catalog No. PIPA5100929
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PIPA5100929 100 μL
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Catalog No. PIPA5100929 Supplier Invitrogen™ Supplier No. PA5100929
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total LRRN1.

Leucine-rich repeat neuronal 1 (LRRN1) is a gene located on chromosome 3q23, which encodes a transmembrane protein belonging to the leucine-rich repeat (LRR) family. This protein plays a significant role in neural development and synaptic plasticity due to its involvement in cell-cell adhesion and signaling pathways. LRRN1 has been implicated in brain development processes, especially in synapse organization and neuronal differentiation. Its expression is primarily localized to the central nervous system, indicating its importance in neurodevelopmental functions. Research has highlighted LRRN1's potential involvement in cognitive functions, and alterations in its expression have been associated with various neurological disorders. Additionally, LRRN1 is thought to contribute to the establishment of neuronal networks by modulating interactions between neurons through extracellular matrix components. Current studies are exploring its contributions to neuropathological conditions, providing insights into its relevance in brain health and disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRRN1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene LRRN1
Gene Accession No. Q32Q07, Q61809, Q6UXK5
Gene Alias 2810047E21Rik; fibronectin type III, immunoglobulin and leucine rich repeat domains 3; FIGLER3; Kiaa1497; leucine rich repeat neuronal 1; leucine rich repeat protein 1, neuronal; leucine-rich repeat neuronal protein 1; LRN; Lrrn1; Nbla10449; Neuronal leucine-rich repeat protein 1; NLRR-1; UNQ693/PRO1338
Gene Symbols LRRN1
Host Species Rabbit
Immunogen A synthesized peptide derived from human LRRN1(Accession Q6UXK5), corresponding to amino acid residues K671-W716.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16979, 500280, 57633
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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