LRRTM2 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-1746	100 μL

Catalog No. 50-198-1746 Supplier Bioss Supplier No. BS11877R

Description

Rabbit Polyclonal Antibody

The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.

Specifications

• Antigen: LRRTM2
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: LRRTM2
• Gene Accession No.: O43300
• Gene Alias: AI851755; BB129880; C630011A14Rik; KIAA0416; leucine rich repeat transmembrane neuronal 2; Leucine-rich repeat neuronal 2 protein; leucine-rich repeat transmembrane neuronal 2 protein; Leucine-rich repeat transmembrane neuronal protein 2; LRRN2; Lrrtm2; mKIAA0416
• Gene Symbols: LRRTM2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human LRRTM2.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 26045
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG