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Invitrogen™ LRWD1 Polyclonal Antibody
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Catalog No. PIPA570121
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100 μL
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Catalog No. Quantity
PIPA570121 100 μL
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Catalog No. PIPA570121 Supplier Invitrogen™ Supplier No. PA570121
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 85%; Dog: 92%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 92%; Rabbit: 92%; Rat: 85%; Yeast: 100%.

Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRWD1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene LRWD1
Gene Accession No. 0
Gene Alias 1200011O22Rik; AU042569; AW548074; CENP-33; Centromere protein 33; leucine rich repeats and WD repeat domain containing 1; leucine-rich repeat and WD repeat-containing protein 1; leucine-rich repeats and WD repeat domain containing 1; LOC304396; Lrwd1; ORCA; ORC-associated protein; Origin recognition complex-associated protein; similar to hypothetical protein DKFZp434K1815; testicular tissue protein Li 4
Gene Symbols LRWD1
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of rat LRWD1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 304396
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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