Invitrogen™ LRWD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570121

Catalog No. PIPA570121

Description

This target displays homology in the following species: Cow: 85%; Dog: 92%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 92%; Rabbit: 92%; Rat: 85%; Yeast: 100%.

Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.

Specifications

• Antigen: LRWD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LRWD1
• Gene Alias: 1200011O22Rik; AU042569; AW548074; CENP-33; Centromere protein 33; leucine rich repeats and WD repeat domain containing 1; leucine-rich repeat and WD repeat-containing protein 1; leucine-rich repeats and WD repeat domain containing 1; LOC304396; Lrwd1; ORCA; ORC-associated protein; Origin recognition complex-associated protein; similar to hypothetical protein DKFZp434K1815; testicular tissue protein Li 4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 304396
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: 0
• Gene Symbols: LRWD1
• Immunogen: synthetic peptide directed towards the middle region of rat LRWD1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG