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Invitrogen™ LRWD1 Polyclonal Antibody
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Catalog No. PIPA532010
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100 μL
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PIPA532010 100 μL
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Catalog No. PIPA532010 Supplier Invitrogen™ Supplier No. PA532010
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, HepG2. Predicted reactivity: Rhesus Monkey (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRWD1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene LRWD1
Gene Accession No. Q9UFC0
Gene Alias 1200011O22Rik; AU042569; AW548074; CENP-33; Centromere protein 33; leucine rich repeats and WD repeat domain containing 1; leucine-rich repeat and WD repeat-containing protein 1; leucine-rich repeats and WD repeat domain containing 1; LOC304396; Lrwd1; ORCA; ORC-associated protein; Origin recognition complex-associated protein; similar to hypothetical protein DKFZp434K1815; testicular tissue protein Li 4
Gene Symbols LRWD1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human LRWD1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 222229
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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