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Invitrogen™ LRWD1 Polyclonal Antibody
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Catalog No. PIPA554380
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100 μL
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Catalog No. Quantity
PIPA554380 100 μL
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Catalog No. PIPA554380 Supplier Invitrogen™ Supplier No. PA554380
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PFLTVNDNLK VSFLLPTLRK VNGKDASSTY SQVENLNREL TSRVTAHWEK FMATLGPEEE AEKAQADFVK SAVRD Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.

Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRWD1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LRWD1
Gene Accession No. Q9UFC0
Gene Alias 1200011O22Rik; AU042569; AW548074; CENP-33; Centromere protein 33; leucine rich repeats and WD repeat domain containing 1; leucine-rich repeat and WD repeat-containing protein 1; leucine-rich repeats and WD repeat domain containing 1; LOC304396; Lrwd1; ORCA; ORC-associated protein; Origin recognition complex-associated protein; similar to hypothetical protein DKFZp434K1815; testicular tissue protein Li 4
Gene Symbols LRWD1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LRWD1. Recombinant protein control fragment (Product #RP-92783).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 222229
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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