Invitrogen™ LSM11 Monoclonal Antibody (OTI2G7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527243

Catalog No. PIMA527243

Description

LSM11 Monoclonal Antibody for Western Blot, IHC (P)

LSm11 is a 360 amino acid protein that localizes to the nucleus and belongs to the LSm subfamily of snRNP Sm proteins. Containing an N-terminal domain that is necessary for pre-mRNA cleavage, LSm11 functions to binds specifically to U7 snRNA and is thought to play a role in cell cycle regulation and cell growth. The gene encoding LSm11 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Specifications

• Antigen: LSM11
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P83369
• Gene Symbols: LSM11
• Immunogen: Full length human recombinant protein of LSM11 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2G7
• Conjugate: Unconjugated
• Gene: LSM11
• Gene Alias: 2210404M20Rik; AV079530; FLJ38273; Lsm11; LSM11, U7 small nuclear RNA associated; RGD1565523; U7 snRNA-associated Sm-like protein LSm11; U7 snRNP-specific Sm-like protein LSM11
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 134353
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid