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Invitrogen™ LSM11 Polyclonal Antibody
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Catalog No. PIPA596709
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100 μL
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PIPA596709 100 μL
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Catalog No. PIPA596709 Supplier Invitrogen™ Supplier No. PA596709
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RRGPGRSRKA PRNVLTRMPL HEGSPLGELH RCIREGVKVN VHIRTFKGLR GVCTGFLVAF DKFWNMALTD VDETYRKPVL GKAYERDSSL TLTRLFDRLK LQDSSKKEAD SKSAVEDSTL SRYSQTSTWK LASVWGRADT GRGSHKRSRS VPSSLQASAR EESRSELSGR TTRTDGSSVG GTFSRATTLS RGQSRKKKRK PKVDYQQVFT RHINQIFIRG ENVLLVHLAQ; Positive Samples: Jurkat, HepG2, MCF7, HL-60, Rat brain, Rat pancreas; Cellular Location: Nucleus.

LSm11 is a 360 amino acid protein that localizes to the nucleus and belongs to the LSm subfamily of snRNP Sm proteins. Containing an N-terminal domain that is necessary for pre-mRNA cleavage, LSm11 functions to binds specifically to U7 snRNA and is thought to play a role in cell cycle regulation and cell growth. The gene encoding LSm11 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LSM11
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LSM11
Gene Accession No. P83369
Gene Alias 2210404M20Rik; AV079530; FLJ38273; Lsm11; LSM11, U7 small nuclear RNA associated; RGD1565523; U7 snRNA-associated Sm-like protein LSm11; U7 snRNP-specific Sm-like protein LSM11
Gene Symbols LSM11
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 131-360 of human LSM11 (NP_7757621).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 134353, 501688
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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