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Invitrogen™ LST1 Polyclonal Antibody
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Catalog No. FEPA5145217
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100 μL
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FEPA5145217 100 μL
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Catalog No. FEPA5145217 Supplier Invitrogen™ Supplier No. PA5145217
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RLPVPSSEGP DLRGRDKRGT KEDPRADYAC IAENKP Antigen sequence identity: Mouse 44%; Rat 51%.

LST1 (leukocyte-specific transcript, also known as B144) is expressed in cells of myeloid/erythroid lineage (monocytes, granulocytes, dendritic cells, platelets, erythrocytes). At least 14 alternatively spliced variants (LST1/A - LST1/N) can be detected; some of them (LST1/A, B, C, G, I, K) are transmembrane cell surface-exposed forms, the other are soluble. LST1 induces production of long, thin filopodia in dendritic cells, has an inhibitory effect on lymphocyte proliferation and may have an immunomodulatory role. LST1/A is an 11 kDa transmembrane adaptor present in membrane rafts and forms spontaneously covalent homodimers. Its intracellular domain contains two tyrosine motifs, one of them being an ITIM very similar to such motifs in Siglec.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LST1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LST1
Gene Accession No. O00453
Gene Alias B144; D6S49E; DAAP-90L16.2; leukocyte specific transcript 1; leukocyte-specific transcript 1 protein; LST1; LST-1; lymphocyte antigen 117; MGC119006; MGC119007; Protein B144
Gene Symbols LST1
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 61-96.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7940
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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