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Invitrogen™ LTB Polyclonal Antibody
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Catalog No. PIPA542713
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100 μL
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PIPA542713 100 μL
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Catalog No. PIPA542713 Supplier Invitrogen™ Supplier No. PA542713
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Rabbit Polyclonal Antibody

Peptide sequence: AVPITVLAVL ALVPQDQGGL VTETADPGAQ AQQGLGFQKL PEEEPETDLS Sequence homology: Guinea Pig: 79%; Horse: 91%; Human: 100%; Rabbit: 100%.

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
TRUSTED_SUSTAINABILITY

Specifications

Antigen LTB
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene LTB
Gene Accession No. Q06643
Gene Alias AI662801; LTB; LTbeta; LT-beta; lymphotoxin B; lymphotoxin beta; lymphotoxin beta (TNF superfamily, member 3); lymphotoxin-beta; p33; TNF superfamily member 3; Tnfc; TNF-C; Tnfsf3; TNLG1C; tumor necrosis factor C; tumor necrosis factor ligand 1C; tumor necrosis factor ligand superfamily member 3
Gene Symbols LTB
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human LTB (aa 35-84).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4050
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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