Invitrogen™ LTB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575247

Catalog No. PIPA575247

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Specifications

• Antigen: LTB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LTB
• Gene Alias: AI662801; LTB; LTbeta; LT-beta; lymphotoxin B; lymphotoxin beta; lymphotoxin beta (TNF superfamily, member 3); lymphotoxin-beta; p33; TNF superfamily member 3; Tnfc; TNF-C; Tnfsf3; TNLG1C; tumor necrosis factor C; tumor necrosis factor ligand 1C; tumor necrosis factor ligand superfamily member 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16994, 361795, 4050
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P41155, Q06643
• Gene Symbols: LTB
• Immunogen: Synthetic peptide corresponding to amino acids 200-244 of Human LT-beta.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG