Invitrogen™ LTK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595099

Catalog No. PIPA595099

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human THP-1 whole cell, human Caco-2 whole cell, human K562 whole cell, human Jurkat whole cell, human MDA-MB-453 whole cell, human U2OS whole cell, human PC-3 whole cell, rat thymus tissue, rat brain tissue, mouse brain tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

LTK (TYK1), ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the Insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B-lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domain of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.

Specifications

• Antigen: LTK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LTK
• Gene Alias: EC 2.7.1.112; EC 2.7.10.1; leukocyte receptor tyrosine kinase; leukocyte tyrosine kinase; leukocyte tyrosine kinase receptor; Ltk; Protein tyrosine kinase 1; TYK1; tyrosine kinase-1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4058
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P29376
• Gene Symbols: LTK
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LTK (850-864aa RGLQPQNLWNPTYRS).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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