Invitrogen™ LUM Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547410

Catalog No. PIPA547410

Description

In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant mouse Lumican is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Specifications

• Antigen: LUM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LUM
• Gene Alias: keratan sulfate proteoglycan lumican; KSPG lumican; Lcn; Ldc; Lum; Lumican; Lumican precursor; lumican proteoglycan; SLRR2D
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4060
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P51884
• Gene Symbols: LUM
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Lumican Gln19-Asn338.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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