Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ LW 6

Tocris Bioscience™ LW 6
GREENER_CHOICE

Catalog No. 632250
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α

LW 6 is a malate dehydrogenase-2 (MDH2) inhibitor (IC50 = 6.3 μM). Also inhibits HIF-1α. Prevents accumulation of HIF-1α in Hep3B cells under hypoxic conditions (IC50 = 2.6 μM) with resulting decrease in expression of HIF-1α target genes VEGF and EPO. Inhibits proliferation of activated human T cells ex vivo.

Specifications

Chemical Name or Material Methyl 4-hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7 ]dec-1-ylphenoxy)acetyl]amino]benzoate
CAS 934593-90-5
Quantity 50 mg
Target Dehydrogenase Inhibitors
Molecular Formula C26H29NO5
Purity 0.98
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.