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Invitrogen™ LXR beta Recombinant Rabbit Monoclonal Antibody (PSH0-56)
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Catalog No. PIMA547617
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100 μL
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PIMA547617 100 μL
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Catalog No. PIMA547617 Supplier Invitrogen™ Supplier No. MA547617
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Description

Rabbit Recombinant Monoclonal Antibody

Sequence Similarities: 83% Mouse/Rat Tissue Specificity: Ubiquitous Positive control: SW480 cell lysate, HepG2 cell lysate, PC-3M cell lysate, A549 cell lysate, HeLa cell lysate, HT-29 cell lysate, HCT116 cell lysate, HEK-293 cell lysate, mouse brain tissue lysate, mouse liver tissue lysate, rat liver tissue lysate, C2C12, HCT116. Subcellular location: Nucleus.

The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LXR beta
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone PSH0-56
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene NR1H2
Gene Accession No. P55055, Q60644, Q62755
Gene Alias AI194859; liver X nuclear receptor beta; liver X receptor beta; LX receptor beta; LXR; LXR beta; LXRB; LXR-b; LXRbeta; NER; NER1; NER-I; Nr1h2; NR1H2 protein; nuclear orphan receptor LXR-beta; nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; nuclear receptor subfamily 1, group H, member 2; OR-1; Orphan nuclear receptor OR-1; oxysterols receptor LXR-beta; Retinoid X receptor-interacting protein No.15; RIP15; steroid hormone-nuclear receptor NER; ubiquitous receptor; ubiquitously-expressed nuclear receptor; ubiquitously-expressed nuclear receptor 2; UNR; Unr2; UR
Gene Symbols NR1H2
Host Species Rabbit
Immunogen Synthetic peptide within human lxr beta aa 50-100/460.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22260, 58851, 7376
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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