Invitrogen™ LXR beta Recombinant Rabbit Monoclonal Antibody (PSH0-56)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547617

Catalog No. PIMA547617

Description

Sequence Similarities: 83% Mouse/Rat Tissue Specificity: Ubiquitous Positive control: SW480 cell lysate, HepG2 cell lysate, PC-3M cell lysate, A549 cell lysate, HeLa cell lysate, HT-29 cell lysate, HCT116 cell lysate, HEK-293 cell lysate, mouse brain tissue lysate, mouse liver tissue lysate, rat liver tissue lysate, C2C12, HCT116. Subcellular location: Nucleus.

The liver X receptors, LXRA and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements.

Specifications

• Antigen: LXR beta
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P55055, Q60644, Q62755
• Gene Symbols: NR1H2
• Immunogen: Synthetic peptide within human lxr beta aa 50-100/460.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Clone: PSH0-56
• Conjugate: Unconjugated
• Gene: NR1H2
• Gene Alias: AI194859; liver X nuclear receptor beta; liver X receptor beta; LX receptor beta; LXR; LXR beta; LXRB; LXR-b; LXRbeta; NER; NER1; NER-I; Nr1h2; NR1H2 protein; nuclear orphan receptor LXR-beta; nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; nuclear receptor subfamily 1, group H, member 2; OR-1; Orphan nuclear receptor OR-1; oxysterols receptor LXR-beta; Retinoid X receptor-interacting protein No.15; RIP15; steroid hormone-nuclear receptor NER; ubiquitous receptor; ubiquitously-expressed nuclear receptor; ubiquitously-expressed nuclear receptor 2; UNR; Unr2; UR
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 22260, 58851, 7376
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid