Invitrogen™ Ly-108 Recombinant Rabbit Monoclonal Antibody (002), APC

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA546741

Catalog No. PIMA546741

Description

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly-108 (Met1-Met226) and conjugated with APC under optimum conditions, the unreacted APC was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6), is expressed on NK cells, B cells, and T cells. Engagement of the Ly108 receptor enhances NK cell activity and increases the expression of IFN-gamma. This receptor plays a role in the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. In Ly108 knock-out mice, CD4+ T cells show a diminished ability to produce IL-4 and exhibit defective neutrophil functions, indicating the importance of Ly108 in immune regulation and cellular function. Overall, Ly108 is crucial for modulating immune responses and maintaining effective immune cell activity.

Specifications

• Antigen: Ly-108
• Classification: Recombinant Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.5% BSA and 0.09% sodium azide
• Gene Accession No.: Q96DU3
• Gene Symbols: SLAMF6
• Immunogen: Recombinant protein ecoding Human Ly-108 (Met1-Met226).
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry
• Clone: 002
• Conjugate: APC
• Gene: SLAMF6
• Gene Alias: Activating NK receptor; CD352; KAL1; KAL1b; KALI; KALIb; Ly108; Lymphocyte antigen 108; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTBA; NTB-A; NTBA receptor; RGD1561848; SF2000; SLAM family member 6; Slamf6; UNQ6123/PRO20080
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 114836
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov