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Invitrogen™ Ly-108 Recombinant Rabbit Monoclonal Antibody (002), APC
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Catalog No. PIMA546741
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100 Tests
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PIMA546741 100 Tests
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Catalog No. PIMA546741 Supplier Invitrogen™ Supplier No. MA546741
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Description

Rabbit Recombinant Monoclonal Antibody

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly-108 (Met1-Met226) and conjugated with APC under optimum conditions, the unreacted APC was removed. Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6), is expressed on NK cells, B cells, and T cells. Engagement of the Ly108 receptor enhances NK cell activity and increases the expression of IFN-gamma. This receptor plays a role in the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. In Ly108 knock-out mice, CD4+ T cells show a diminished ability to produce IL-4 and exhibit defective neutrophil functions, indicating the importance of Ly108 in immune regulation and cellular function. Overall, Ly108 is crucial for modulating immune responses and maintaining effective immune cell activity.
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Specifications

Antigen Ly-108
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone 002
Concentration 100 μg/mL
Conjugate APC
Formulation PBS with 0.5% BSA and 0.09% sodium azide
Gene SLAMF6
Gene Accession No. Q96DU3
Gene Alias Activating NK receptor; CD352; KAL1; KAL1b; KALI; KALIb; Ly108; Lymphocyte antigen 108; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTBA; NTB-A; NTBA receptor; RGD1561848; SF2000; SLAM family member 6; Slamf6; UNQ6123/PRO20080
Gene Symbols SLAMF6
Host Species Rabbit
Immunogen Recombinant protein ecoding Human Ly-108 (Met1-Met226).
Purification Method Protein A
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114836
Target Species Human
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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